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Carnitine

Vitamin E and L-Carnitine in Patients with End-stage Renal Disease

Posted January 12, 2014

In a prospective study involving 20 patients with end-stage renal disease on chronic hemodialysis with intradialytic complications such as hypotension, muscle cramp, nausea, vomiting, and headache, treatments with vitamin E (200 IU/d) and L-carnitine (500 mg/d), alone and in combination, were found to be effective in reducing these intradialytic complications.

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Carnitine’s Sports Value More than Just Energy Production

Posted August 22, 2013

Carnitine is an important sports nutrition compound due to its role in energy production, but its consequential benefits to cardiovascular health and function may also help improve exercise performance and recovery.

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L-Carnitine Improves Sperm Motility and Vitality

Posted August 3, 2013

In a study involving 22 male infertile patients, the effects of l-carnitine applied to sperm samples during cyropreservation (a process that influences reproductive outcomes in assisted reproductive outcomes of assisted reproductive technologies, but that significantly decreases sperm quality) as compared to sperm cyropreserved without L-carnitine, was examined.

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Children With Heart Defects May Benefit From Carnitine Supplement

Posted May 12, 2013

A common nutritional supplement may be part of the magic in improving the survival rates of babies born with heart defects, researchers report. Carnitine, a compound that helps transport fat inside the cell powerhouse where it can be used for energy production, is currently used for purposes ranging from weight loss to chest pain.

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Acetyl-L-Carnitine in the Treatment of Amyotrophic Lateral Sclerosis (ALS)

Posted May 8, 2013

In a pilot, double-blind, placebo-controlled, parallel group study involving patients between the ages of 40 and 70 years with definite or probable amyotrophic lateral sclerosis (ALS), who were self-sufficient (able to swallow, cut food/handle utensils, walk), with forced vital capacity of > 80%, who were followed for 48 weeks, supplementation with acetyl-L-carnitine (ALC), 3 g/d, added to riluzole 100 mg/d, was found to be “effective, well-tolerated and safe.”

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Effects of Carnitine Supplementation in Walking Performance in Persons with Intermittent Claudication

Posted April 27, 2013

In a systematic review which involved analysis of results of 17 studies (8 parallel randomized controlled trials, 5 crossover RCTs, 5 pre-test/post-test trials), a small or moderate improvement in walking performance was found to be associated with supplementation with propionyl-L-carnitine (PLC) or carnitine, in patients with intermittent claudication.

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Study: Lower Dosage Carnipure Supplementation May Have Effects on Weight Management

Posted February 27, 2013

A new study confirmed the role of Carnipure (l-carnitine from supplier Lonza) supplementation combined with healthy lifestyle education on the success of weight management programs. The primary objective of this pilot, double-blind, randomized, placebocontrolled clinical trial conducted by the Japanese Clinical Research Organization Souken was to examine the effect of Carnipure tartrate providing a low dose of L-carnitine on weight management and energy metabolism-related parameters in overweight but healthy human subjects.

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Antioxidant Nutritional Supplement including Carnitines May Improve Sperm

Posted December 18, 2012

An open-label study involving 114 infertile men diagnosed with idiopathic astenoteratozoospermia for 18 months or longer found that a nutritional supplement may improve important parameters of sperm count.

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Propionyl-L-carnitine May Improve Mild Ulcerative Colitis

Posted November 19, 2012

A clinical study involving 14 patients with mild to moderate ulcerative colitis (UC) or Crohn’s disease (CD) found that supplementation with propionyl-L-carnitine hydrochloride (PLC) may improve symptoms and outcomes in such patients.

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Propionyl-L-Carnitine Hydrochloride May Improve IBD

Posted October 29, 2012

A clinical study involving 14 patients suffering from mild to moderate ulcerative colitis (UC) or Crohn’s disease (CD) found that propionyl-L-carnitine hydrochloride (PLC) may improve endoscopic and histological activity.

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