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Coenzyme Q10

Coenzyme Q10 Supplementation and Electron Transport Chain Activity and Mitochondrial Oxidative Stress

Posted March 7, 2014

In a study involving human SH-SY5Y neuronal cells with 1mM para-aminobenzoic acid (PABA) which induced a 54% decrease in cellular coenzyme Q10 status, treatment with 2.5 microM coenzyme Q10 for a period of 5 days significantly decreased the level of mitochondrial superoxide in the coenzyme Q10 deficient neurons, and 5 microM of coenzyme Q10 restored mitochondrial membrane potential to 90% of the control levels, while 10 microM coQ10 was only partially effective at restoring mitochondrial electron transport chain (ETC) enzyme activities.

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Relationship between Physical Activity and Coenzyme Q10 Status in the Elderly

Posted March 4, 2014

In a study involving a cohort of healthy, community-dwelling elderly people who were divided according to gender and fitness, people with higher levels of functional capacity were found to have lower levels of cholesterol and lipid peroxidation, accompanied with higher levels of coenzyme Q10 in plasma, and the ratio of coenzyme Q10/cholesterol and coenzyme Q10/LDL increased in these people as well.

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Coenzyme Q10 and Patients with Sickle Cell Anemia

Posted February 13, 2014

In a study involving sickle cell patients in the Chhattisgarh tribal population between the ages of 10 and 55 years of age, supplementation with coenzyme Q10 (200 mg/d) was found to improve hematological parameters and decrease inflammation (C-reactive protein) and TBARS levels.

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Coenzyme Q10 and Antioxidants in Patients with Sanfilippo Disease

Posted January 12, 2014

In a study involving patients with Sanfilippo syndrome, decreased basal levels of coenzyme q10 were found in fibroblasts of patients, but no dysfunction in coq10 biosynthesis was found, suggesting a secondary coQ10 deficiency in patients with Sanfilippo A fibroblasts.

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Can CoQ10 Help You Beat Chronic Depression?

Posted January 9, 2014

It’s well established that Coenzyme Q10 (CoQ10) is beneficial for maintaining a healthy heart and protecting the brain, but a new study indicates CoQ10 may be an untapped aid for those with chronic depression.

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How can CoQ10 make it easier to quit cigarettes?

Posted December 31, 2013

No matter whom you are, your heart beats about 100,000 times a day, fueling your entire cardiovascular system. When coenzyme Q10 (CoQ10) levels get depleted, your heart strains to get its job done and your entire body suffers. This manifests and results in what seem to be “mysterious symptoms” that most allopathic doctors just can’t put their finger on, so they put a “prescription” on it instead. Are you experiencing chronic fatigue, numbing dull pains or decreases in mental functions? This is not just about smokers and the elderly, as this addresses every human being whose heart beats one million times in ten days. It’s time to consider natural solutions to seemingly “complex problems.”

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Coenzyme Q10, Alpha-Tocopherol, and Oxidative Stress in Male Infertility

Posted December 12, 2013

In a study involving men with infertility, incorporating an oxidative stress assessment, as well as measuring levels of coenzyme 10-TOTAL and alpha-tocopherol in the seminal fluid and plasma may play a significant role in diagnosing and determining targeted therapeutic treatment in men with infertility.

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Supplementation with Coenzyme Q10 Improves Statin-induced Myopathy

Posted December 3, 2013

In this review, the authors analyze the effects of coenzyme Q10 supplementation on myopathy induced by the use of statin drugs. Results found a significant relationship between statin intake and decreased serum levels of coenzyme Q10, a reduction in symptoms of myalgia (in a few studies) and an improvement in serum coenzyme Q10 levels.

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Can Higher Doses of CoQ10 Protect You From This Devastating Disease?

Posted November 25, 2013

We’ve long known that CoenzymeQ10, also known as CoQ10, is critical for heart health, but here’s an exciting new reason to consider taking it: CoQ10 may actually help protect your brain from Alzheimer’s. The potent antioxidant attenuates the type brain damage that leads to Alzheimer’s disease, say researchers at Hanyang University College of Medicine, who tested CoQ10 on animals with Alzheimer’s-type brain damage.

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Effects of coenzyme Q10 supplementation (300 mg/day) on antioxidation and anti-inflammation in coronary artery disease patients during statins therapy: a randomized, placebo-controlled trial

Posted November 6, 2013

High oxidative stress and chronic inflammation can contribute to the pathogenesis of coronary artery disease (CAD). Coenzyme Q10 is an endogenous lipid-soluble antioxidant. Statins therapy can reduce the biosynthesis of coenzyme Q10. The purpose of this study was to investigate the effects of a coenzyme Q10 supplement (300 mg/d; 150 mg/b.i.d) on antioxidation and anti-inflammation in patients who have CAD during statins therapy.

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