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Elderly Men

Relationship Between Vitamin D and Frailty in Elders

Posted June 27, 2013

In a cross-sectional analysis of 1,659 Australian men (from the Concord Health and Ageing in Men Project in Sydney), 1,25-dihydroxyvitamin D and 25-hydroxyvitamin D levels were independently associated with frailty in older men.

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BACE1 inhibitory activity of fungal endophytic extracts from Malaysian medicinal plants

Posted April 30, 2012

BACE1 was found to be the major beta-secretase in neurons and its appearance and activity were found to be elevated in the brains of AD patients. Fungal endophytic extracts for BACE1 inhibitory activity and cytotoxicity against PC-12 (a rat pheochromocytoma with neuronal properties) and WRL68 (a non-tumorigenic human hepatic) were investigated.

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