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Fibrosis

Effects of Carissa opaca fruits extracts on oxidative pulmonary damages and fibrosis in rats

Posted January 31, 2014

Carissa opaca is a Pakistani fruit, traditionally used in the treatment of various human ailments including asthma and pulmonary damage. The present study investigated the protective effects of Carissa opaca against CCl4-induced oxidative stress in rat lungs.

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Oleanolic acid attenuates renal fibrosis in mice with unilateral ureteral obstruction via facilitating nuclear translocation of Nrf2

Posted January 8, 2014

Renal interstitial fibrosis is a common final pathological process in the progression of kidney disease. This is primarily due to oxidative stress, which contributes to renal inflammation and fibrosis. Nuclear factor-erythroid-2-related factor 2 (Nrf2) is known to coordinate induction of genes that encode antioxidant enzymes. We investigated the effects of oleanolic acid, a known Nrf2 activator, on oxidative stress-induced renal inflammation and fibrosis.

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Clinical Effects of Diet Supplementation with DHA in Pediatric Patients with Cystic Fibrosis

Posted October 6, 2013

In a study involving pediatric patients with cystic fibrosis, supplementation with the omega-3 fatty acid, DHA, for a period of 6 months, was found to be associated with improvements in clinical condition of patients, as well as reductions in pulmonary and intestinal inflammation. One g/10 kg/d was adminstered for the first month, followed by 250 mg/10 kg/d for the following 5 months.

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Sunshine hormone, vitamin D, may offer hope for treating liver fibrosis

Posted April 27, 2013

Liver fibrosis results from an excessive accumulation of tough, fibrous scar tissue and occurs in most types of chronic liver diseases. In industrialized countries, the main causes of liver injury leading to fibrosis include chronic hepatitis virus infection, excess alcohol consumption and, increasingly, nonalcoholic steatohepatitis (NASH).

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Chinese Herbs Show Promise for Lung Cancer, Flu, and Idiopathic Pulmonary Fibrosis

Posted October 23, 2012

Chinese herbs, including JHQG, BFXL, and BFHX, may show significant benefits for patients with non-small cell lung cancer, idiopathic pulmonary fibrosis, and influenza. In three separate studies, researchers from China Academy of Chinese Medical Science in Beijing analyzed the health benefits of Chinese herbs on patients with NSCLC, IPF, and seasonal influenza.

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Molecular Insights of Curcumin in Conjunction with Acupuncture in Hepatic Fibrosis

Posted July 31, 2012

A randomized controlled study involving 60 Sprague-Dawley male rats with chemically induced liver fibrosis found potent benefits to combining curcumin and acupuncture on a molecular level. Rats were randomly divided into control, model, sham, acupuncture, curcumin and combination treatment groups.

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Increased Fitness, Not Weight Loss, Improves Mortality

Posted April 30, 2012

Good news for exercise junkies who don’t quite look like all-American swimmer Michael Phelps or the ultralean marathoners crossing the New York City finish line: Fitness appears to trump weight loss when it comes to reducing all-cause and cardiovascular mortality. Data from a large longitudinal study show that maintaining and improving physical-fitness levels were associated with lower risks of all-cause and cardiovascular disease mortality, whereas changes in body-mass index (BMI) were not.

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Steroid from Mustard Can Help Improve Physical Fitness: A North Carolina Study

Posted April 30, 2012

In addition to adding an excellent and pleasant flavor to meals, our traditional herb mustard can help one go from fat to fit. A recent research conducted by Debora Esposito and colleagues from the Human Health Institute at North Carolina University in Kannapolis, USA, suggested that a compound called homobrassinolide, found in plants like mustard, helps to increase the lean body mass, muscle mass and physical performance in mammals.

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