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Comprehensive assessment of phenolics and antiradical potential of Rumex hastatus D. Don. roots

Posted February 9, 2014

Roots of Rumex hastatus (Polygonaceae) are traditionally used for the treatment of various ailments including liver and lung diseases. In this study, various solvent extracts of R. hastatus roots, like methanolic, n-hexane, ethyl acetate, chloroform, butanol and aqueous fractions were assessed through their antioxidant properties in vitro and determination of phenolic contents.

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Preliminary antimycobacterial study on selected Turkish plants (Lamiaceae) against Mycobacterium tuberculosis and search for some phenolic constituents

Posted December 23, 2013

The global resurgence of tuberculosis is a significant threat. Lamiaceae members have been used in folk remedies for centuries. This study was designed to assess the in-vitro antimycobacterial activity of eighteen crude extracts from six plants (Lamiaceae) and to characterize their phenolic and flavonoid compounds.

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A phenolic ester from Aglaia loheri leaves reveals cytotoxicity towards sensitive and multidrug-resistant cancer cells

Posted October 28, 2013

Bioactivity-guided fractionation of extracts of Aglaia loheri Blanco (Meliaceae) yielded a cytotoxic isolate, termed Maldi 531.2[M + H]+. This phenolic ester was further investigated for its in vitro cytotoxicity toward human CCRF-CEM leukemia cells and their multi-drug resistant (MDR) subline, CEM/ADR5000. The intrinsic mitochondrial membrane potential (DeltaPsim) and induction of apoptosis by this isolate were evaluated.

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Antioxidant potential, cytotoxic activity and total phenolic content of Alpinia pahangensis rhizomes

Posted October 2, 2013

Alpinia pahangensis, a wild ginger distributed in the lowlands of Pahang, Malaysia, is used by the locals to treat flatulence. In this study, the antioxidant and cytotoxic activities of the crude aqueous methanol and fractionated extracts of Alpinia pahangensis against five different cancer and one normal cell lines were investigated. The total phenolic content of each extract and its fractions were also quantified. This is the first report on the antioxidant and cytotoxic activities of Alpinia pahangensis extract.

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Phenolic compounds from Rosemary (Rosmarinus officinalis L.) attenuate oxidative stress and reduce blood cholesterol concentrations in diet-induced hypercholesterolemic rats

Posted February 4, 2013

Phenolic compounds combine antioxidant and hypocholesterolemic activities and, consequently, are expected to prevent or minimize cardiometabolic risk.

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Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L

Posted November 16, 2012

The aim of this study was to screen various solvent extracts of whole plant of Torilis leptophylla to display potent antioxidant activity in vitro and in vivo, total phenolic and flavonoid contents in order to find possible sources for future novel antioxidants in food and pharmaceutical formulations.

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Common Sources of the Dietary Supplement Phosphatidylserine

Posted April 30, 2012

Phosphatidylserine is a type of phospholipid located within cell membranes. It is essential for cell signaling, nerve function and the coordination of enzymatic activity. Phosphatidylserine is available as a dietary supplement, but small quantities naturally occur in meat, fish and legumes. Current research indicates that the supplement may be useful in treating conditions affecting memory, nerves and behavior.

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