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Artificial Sweeteners – Adverse Events

Posted April 26, 2017

A review and biological risk assessment of sodium saccharin.

Artificial Sweetener(s): Saccharin

Adverse Events: Cancer

Chappel, C. I. “A Review and Biological Risk Assessment of Sodium Saccharin.” [In eng]. Regul Toxicol Pharmacol 15, no. 3 (Jun 1992): 253-70.

A cancer risk assessment for saccharin.

Artificial Sweetener(s): Saccharin

Adverse Events: Cancer

Carlborg, F. W. “A Cancer Risk Assessment for Saccharin.” [In eng]. Food Chem Toxicol 23, no. 4-5 (Apr-May 1985): 499-506.

Artificial sweeteners and the risk of gastric, pancreatic, and endometrial cancers in Italy.

Artificial Sweetener(s): Saccharin, Aspartame

Adverse Events: No risk for cancer found

Bosetti, C., S. Gallus, R. Talamini, M. Montella, S. Franceschi, E. Negri, and C. La Vecchia. “Artificial Sweeteners and the Risk of Gastric, Pancreatic, and Endometrial Cancers in Italy.” [In eng]. Cancer Epidemiol Biomarkers Prev 18, no. 8 (Aug 2009): 2235-8.

Consumption of artificial sweetener- and sugar-containing soda and risk of lymphoma and leukemia in men and women.

Artificial Sweetener(s): Aspartame

Adverse Events: Inconclusive

Schernhammer, E. S., K. A. Bertrand, B. M. Birmann, L. Sampson, W. C. Willett, and D. Feskanich. “Consumption of Artificial Sweetener- and Sugar-Containing Soda and Risk of Lymphoma and Leukemia in Men and Women.” [In eng]. Am J Clin Nutr 96, no. 6 (Dec 2012): 1419-28.

Intra-uterine exposure to saccharin and risk of bladder cancer in man.

Artificial Sweetener(s): Saccharine

Adverse Events: No risk for cancer found

Jensen, O. M., and C. Kamby. “Intra-Uterine Exposure to Saccharin and Risk of Bladder Cancer in Man.” [In eng]. Int J Cancer 29, no. 5 (May 15 1982): 507-9.

Soft drinks, aspartame, and the risk of cancer and cardiovascular disease.

Artificial Sweetener(s): Aspartame

Adverse Events: Cardiovascular Disease

Aune, D. “Soft Drinks, Aspartame, and the Risk of Cancer and Cardiovascular Disease.” [In eng]. Am J Clin Nutr 96, no. 6 (Dec 2012): 1249-51.

Saccharin: the risks and benefits.

Artificial Sweetener(s): Saccharine

Adverse Events: Cancer

Cohen, B. L. “Saccharin: The Risks and Benefits.” [In eng]. Nature 271, no. 5645 (Feb 09 1978): 492.

The relative risks of saccharin and sucrose ingestions.

Artificial Sweetener(s): Saccharin, Sucrose

Adverse Events: Risks

Walker, A. R. “The Relative Risks of Saccharin and Sucrose Ingestions.” [In eng]. Am J Clin Nutr 32, no. 4 (Apr 1979): 727-8.

Adverse reactions to aspartame: Double-blind challenge in patients from a vulnerable population.

Artificial Sweetener(s): Aspartame

Adverse Events: Mood disorders

Walton, R. G., R. Hudak, and R. J. Green-Waite. “Adverse Reactions to Aspartame: Double-Blind Challenge in Patients from a Vulnerable Population.” [In eng]. Biol Psychiatry 34, no. 1-2 (Jul 1-15 1993): 13-7.

Relative risks of saccharin and calorie ingestion.

Artificial Sweetener(s): Saccharine

Adverse Events: Cancer

Cohen, B. L. “Relative Risks of Saccharin and Calorie Ingestion.” [In eng]. Science 199, no. 4332 (Mar 03 1978): 983.

Aspartame approved despite risks.

Artificial Sweetener(s): Aspartame

Adverse Events: Risk

Smith, R. J. “Aspartame Approved Despite Risks.” [In eng]. Science 213, no. 4511 (Aug 28 1981): 986-7.

A cancer risk assessment for saccharine.

Artificial Sweetener(s): Saccharine.

Adverse Events: Cancer

Carlborg, F. W. “A Cancer Risk Assessment for Saccharin.” [In eng]. Food Chem Toxicol 23, no. 4-5 (Apr-May 1985): 499-506.

Aspartame consumption in relation to childhood brain tumor risk: Results from a case-control study.

Artificial Sweetener(s): Aspartame

Adverse Events: Childhood brain tumor

Gurney, J. G., J. M. Pogoda, E. A. Holly, S. S. Hecht, and S. Preston-Martin. “Aspartame Consumption in Relation to Childhood Brain Tumor Risk: Results from a Case-Control Study.” [In eng]. J Natl Cancer Inst 89, no. 14 (Jul 16 1997): 1072-4.